Nebracetam hydrochloride( WEB 1881 FU hydrochloride )

Catalog No. M26327 CAS No. 1177279-49-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Nebracetam hydrochloride
Note

Research use only, not for human use.
Brief Description

Nebracetam hydrochloride is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration.
Description

Nebracetam hydrochloride is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i.(In Vitro):Nebracetam involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms.
In Vitro

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In Vivo

Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms. Animal Model:Male Wistar rats weighing 200-250 g.Dosage:10, 20 mg/kg.Administration:P.O. (single dose).Result:Able to correct this scopolamine-induced disruption of spatial cognition.
Synonyms

WEB 1881 FU hydrochloride
Pathway

Cell Cycle/DNA Damage
Target

AChR
Recptor

VHL
Research Area

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Indication

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1.Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

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